By David A.D. Parry,John M. Squire
This publication offers the readers with an updated evaluate of the layout, constitution and serve as of a consultant number of fibrous proteins in either future health and affliction. the significance of the α-helical coiled coil, a conformational motif in response to the heptad repeat within the amino acid series of all α-fibrous proteins (and components of a few globular proteins) is underlined by way of 3 Chapters dedicated to its layout, constitution, functionality and topology. particular proteins coated within the textual content and which depend upon the coiled coil for his or her constitution and serve as, comprise the intermediate filament proteins, tropomyosin, myosin, paramyosin, fibrin and individuals of the spectrin superfamily. additionally defined are fibrous proteins in response to the β-pleated sheet and collagen conformations. Recombinant structural proteins, in particular of silk and collagen, are mentioned within the context of constructing new biomaterials with diversified functions.
Established researchers and postgraduate scholars within the fields of protein chemistry, biochemistry and structural biophysics will locate Fibrous Proteins: buildings and Mechanisms to be a useful choice of topical experiences that describe the fundamental advances made within the box of fibrous proteins over the last decade. This publication, written by way of famous specialists within the box, offers a transparent account of the present prestige of fibrous protein examine and, moreover, establishes the foundation for finding out the main acceptable instructions for destiny job, together with the functions of protein engineering and the economic exploitation of latest biomaterials.
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Fibrous Proteins: Structures and Mechanisms (Subcellular Biochemistry) by David A.D. Parry,John M. Squire