By Mark C. Williams,III, L. James Maher
Depite the speedy enlargement of the sphere of biophysics, there are only a few books that comprehensively deal with particular themes during this region. lately, the sphere of unmarried molecule biophysics has built in a short time, and some books particularly treating unmarried molecule tools are starting to look. even though, the promise of unmarried molecule biophysics is to give a contribution to the certainty of particular fields of biology utilizing new equipment. This e-book may concentrate on the explicit subject of the biophysics of DNA-protein interactions, and would come with using new ways, together with either bulk equipment in addition to unmarried molecule equipment. this might make the booklet appealing to an individual operating within the normal zone of DNA-protein interactions, that's after all a much broader marketplace than simply unmarried molecule biophysicists or perhaps biophysicists.
The topic of the publication would be the biophysics of DNA-protein interactions, and should comprise new tools and effects that describe the actual mechanism wherein proteins engage with DNA. for instance, there was a lot fresh paintings at the mechanism wherein proteins look for particular binding websites on DNA. a couple of chapters could be dedicated to experiments and thought that make clear this crucial challenge. we are going to additionally hide proteins that modify DNA homes to facilitate interactions vital for transcription or replication. one other element of the e-book will conceal the biophysical mechanism wherein motor proteins have interaction with DNA. eventually, we are going to conceal better protein-DNA complexes, similar to replication forks, recombination complexes, DNA fix interactions, and their chromatin context.
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Biophysics of DNA-Protein Interactions: From Single Molecules to Biological Systems (Biological and Medical Physics, Biomedical Engineering) by Mark C. Williams,III, L. James Maher