By Oriol Güell
This thesis makes use of a systems-level method of research the mobile metabolism, unveiling new mechanisms and responses that have been most unlikely to arrive with conventional reductionists systems.
The effects suggested right here have a possible program in components like metabolic engineering and illness therapy. they can even be utilized in identifying the accuracy of the gene essentiality of recent genome-scale reconstructions.
Different equipment and methods, in the contexts of structures Biology and the sector referred to as advanced Networks research were utilized during this paintings to teach various positive factors of the robustness of metabolic networks. the explicit concerns addressed the following variety from natural topological aspec
ts of the networks themselves to the stability of biochemical fluxes.
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A Network-Based Approach to Cell Metabolism: From Structure to Flux Balances (Springer Theses) by Oriol Güell